Researchers Claiming To Discover Certain Pattern of Expression Common to Autistic Brain

Researchers Claiming To Discover Certain Pattern of Expression Common to Autisti

A team of researchers, led by Dr. Dan Geschwind, Director of the Center for Autism Research and Treatment at the University of California, Los Angeles (UCLA), has analyzed levels of gene expressions, to determine the synthesis of various proteins with a particular task in the brain tissue.

They observed that children living with autism, showed a marked drop in the gene expression in 2 areas, frontal lobe and the temporal lobe of the cerebral cortex, high order processing zone. The frontal lobe is vital for judgment, creativity, emotion and speech whereas the temporal lobe is responsible for activities such as hearing, language and sound processing.

Additionally, the healthy brains were observed with differences in the gene expressions of around 500 genes between the frontal and temporal lobes whereas the autistic brains have not displayed any deviation in the expressions.

"To see strong signals [that autistic children have] in common tells us there is a lot more hope for the field in some ways and that even though there may be many different causes of autism, there are some shared underlying molecular features. That to me was a big change in the way many of us think about autism”, he explained further.

The Autism Tissue Program, a brain bank registry, the Harvard Brain Bank and the Medical Research Council’s London Brain Bank for Neurodegenerative Disease have provided the brain samples.


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