UK Mice Study Can Result in Alzheimer's Treatment
As per recent reports, it has been revealed that scientists from Britain have successfully discovered a special kind of antibody in mice which results in blocking a characteristic of the potentially disastrous Alzheimer's disease, thereby providing a probable and fresh route for the treatment.
The antibodies, as per researchers, is capable of shutting down a protein dubbed Dkk1 which, as a response, effectively stops the configuration of amyloid plaque in the human brain, which is said to be an important aspect in the development of Alzheimer's disease.
A study carried out in this regard, which has been made available in the recent edition of the Journal of Neuroscience, has revealed that at the time of plaque formation, a loss of association takes place between neurons, which are also called synapses. The lack of connection taking place in the portion of brain known as the hippocampus, which is responsible for handling aspects such as memory and learning, is highly vital and imminent.
While expressing his opinion in this regard, along with mentioning what all can be done in order to tackle the issue, Patricia Salinas, the lead author of the study from the Department of Cell and Developmental Biology of the University College London, said: “These novel findings raise the possibility that targeting this secreted Dkk1 protein could offer an effective treatment to protect synapses against the toxic effect of amyloid-B”.
Most importantly, these sorts of results generally tend to spike up expectations for a treatment in the segment and thereby increasing possibilities of cognitive decline during the initial time of Alzheimer's disease. The research, as of now, has just been carried out in mice and it has been said by more work is yet to be done in the segment so as to reach some burly results.
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